2-Aminopyrimidine-5-carboxylic acid ethyl ester

2-Aminopyrimidine-5-carboxylic acid ethyl ester - Names and Identifiers

Name	ethyl 2-aminopyrimidine-5-carboxylate
Synonyms	EOS-60351 NSC 165511 57401-76-0 5-Carbethoxy-2-pyriMidinaMine ethyl 2-aminopyrimidine-5-carboxylate ETHYL 2-AMINO-5-PYRIMIDINECARBOXYLATE methyl 2-aminopyrimidine-5-carboxylate 2-Aminopyrimidine-5-carboxylic acid ethyl ester 2-Amino-5-pyrimidinecarboxylic acid ethyl ester 2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER 2-Amino-pyrimidine-5-carboxylic acid ethyl ester 5-PyriMidinecarboxylic acid, 2-aMino-, ethyl ester
CAS	57401-76-0
InChI	InChI=1/C6H7N3O2/c1-11-5(10)4-2-8-6(7)9-3-4/h2-3H,1H3,(H2,7,8,9)

2-Aminopyrimidine-5-carboxylic acid ethyl ester - Physico-chemical Properties

Molecular Formula	C7H9N3O2
Molar Mass	167.17
Density	1.261
Melting Point	147-149℃
Boling Point	349℃
Flash Point	165℃
Vapor Presure	0mmHg at 25°C
pKa	1.94±0.10(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.577
MDL	MFCD04114100

2-Aminopyrimidine-5-carboxylic acid ethyl ester - Introduction

Ethyl, also known as acetoxy-2-aminopyrimidine-5-carboxylate (ethyl), its chemical formula is C8H9N3O2.

Nature:
ethyl l is a white crystalline powder. It is almost insoluble in water at room temperature, but can be dissolved in some organic solvents such as ethanol and dichloromethane. It is stable under acidic conditions, but decomposes under alkaline conditions.

Use:
ethyl l widely used in organic synthesis reaction as a raw material and intermediate. It can be used to prepare various drugs, pesticides and photosensitive materials. For example, it can be used for the synthesis of anticancer drugs as well as energy conversion related compounds.

Preparation Method:
The preparation method of ethyl l is relatively simple. A common synthetic method is the reaction of 2-aminopyrimidine with acetic acid and dimethylcarbodiimide to give ethyl carbamate.

Safety Information:
ethyl has higher safety, but still need to pay attention to protective measures. Avoid contact with skin and eyes during operation, and maintain good ventilation conditions. In case of accidental contact, rinse immediately with water and seek medical advice. In addition, it should also be stored in a dark, dry place, away from fire and oxidizing agents.

Last Update：2024-04-09 20:52:54